Radiological and nuclear medicine imaging of gastroenteropancreatic neuroendocrine tumours.
Identifieur interne : 000B13 ( Main/Exploration ); précédent : 000B12; suivant : 000B14Radiological and nuclear medicine imaging of gastroenteropancreatic neuroendocrine tumours.
Auteurs : RBID : pubmed:23582920English descriptors
- KwdEn :
- Diagnostic Imaging (methods), Humans, Intestinal Neoplasms (diagnosis), Intestine, Small, Liver Neoplasms (diagnosis), Liver Neoplasms (secondary), Magnetic Resonance Imaging, Neuroendocrine Tumors (diagnosis), Neuroendocrine Tumors (radionuclide imaging), Neuroendocrine Tumors (secondary), Octreotide (analogs & derivatives), Octreotide (diagnostic use), Pancreatic Neoplasms (diagnosis), Positron-Emission Tomography (methods), Radiopharmaceuticals (diagnostic use), Receptors, Somatostatin, Somatostatin (analogs & derivatives), Somatostatin (diagnostic use), Stomach Neoplasms (diagnosis), Tomography, X-Ray Computed, Ultrasonography.
- MESH :
- chemical , analogs & derivatives : Octreotide, Somatostatin.
- diagnosis : Intestinal Neoplasms, Liver Neoplasms, Neuroendocrine Tumors, Pancreatic Neoplasms, Stomach Neoplasms.
- chemical , diagnostic use : Octreotide, Radiopharmaceuticals, Somatostatin.
- methods : Diagnostic Imaging, Positron-Emission Tomography.
- radionuclide imaging : Neuroendocrine Tumors.
- secondary : Liver Neoplasms, Neuroendocrine Tumors.
- Humans, Intestine, Small, Magnetic Resonance Imaging, Receptors, Somatostatin, Tomography, X-Ray Computed, Ultrasonography.
Abstract
Neuroendocrine tumours (NETs) comprise a heterogeneous group of neoplasms with very varying clinical expression. A functioning NET, for instance in the pancreas, may be very small and yet give rise to severe endocrine symptoms whereas a patient with a small bowel tumour may present with diffuse symptoms and disseminated disease with a palpable bulky liver. Imaging of NETs is therefore challenging and the imaging needs in the various patients are diverse. The basic modalities for NET imaging are computed tomography (CT) or magnetic resonance imaging (MRI) in combination with somatostatin receptor imaging (SMI) by scintigraphy with 111In-labelled octreotide (OctreoScan) or more recently by positron emission tomography (PET) with 68Ga-labelled somatostatin analogues. In this review these various morphological and functional imaging modalities and important methodological aspects are described. Imaging requirements for the various types of NETs are discussed and typical image findings are illustrated.
DOI: 10.1016/j.bpg.2012.12.004
PubMed: 23582920
Links toward previous steps (curation, corpus...)
Le document en format XML
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<author><name sortKey="Sundin, Anders" uniqKey="Sundin A">Anders Sundin</name>
<affiliation wicri:level="1"><nlm:affiliation>Karolinska Institute and Karolinska University Hospital, SE-171 76 Stockholm, Sweden. anders.sundin@ki.se</nlm:affiliation>
<country xml:lang="fr">Suède</country>
<wicri:regionArea>Karolinska Institute and Karolinska University Hospital, SE-171 76 Stockholm</wicri:regionArea>
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<profileDesc><textClass><keywords scheme="KwdEn" xml:lang="en"><term>Diagnostic Imaging (methods)</term>
<term>Humans</term>
<term>Intestinal Neoplasms (diagnosis)</term>
<term>Intestine, Small</term>
<term>Liver Neoplasms (diagnosis)</term>
<term>Liver Neoplasms (secondary)</term>
<term>Magnetic Resonance Imaging</term>
<term>Neuroendocrine Tumors (diagnosis)</term>
<term>Neuroendocrine Tumors (radionuclide imaging)</term>
<term>Neuroendocrine Tumors (secondary)</term>
<term>Octreotide (analogs & derivatives)</term>
<term>Octreotide (diagnostic use)</term>
<term>Pancreatic Neoplasms (diagnosis)</term>
<term>Positron-Emission Tomography (methods)</term>
<term>Radiopharmaceuticals (diagnostic use)</term>
<term>Receptors, Somatostatin</term>
<term>Somatostatin (analogs & derivatives)</term>
<term>Somatostatin (diagnostic use)</term>
<term>Stomach Neoplasms (diagnosis)</term>
<term>Tomography, X-Ray Computed</term>
<term>Ultrasonography</term>
</keywords>
<keywords scheme="MESH" type="chemical" qualifier="analogs & derivatives" xml:lang="en"><term>Octreotide</term>
<term>Somatostatin</term>
</keywords>
<keywords scheme="MESH" qualifier="diagnosis" xml:lang="en"><term>Intestinal Neoplasms</term>
<term>Liver Neoplasms</term>
<term>Neuroendocrine Tumors</term>
<term>Pancreatic Neoplasms</term>
<term>Stomach Neoplasms</term>
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<keywords scheme="MESH" type="chemical" qualifier="diagnostic use" xml:lang="en"><term>Octreotide</term>
<term>Radiopharmaceuticals</term>
<term>Somatostatin</term>
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<keywords scheme="MESH" qualifier="methods" xml:lang="en"><term>Diagnostic Imaging</term>
<term>Positron-Emission Tomography</term>
</keywords>
<keywords scheme="MESH" qualifier="radionuclide imaging" xml:lang="en"><term>Neuroendocrine Tumors</term>
</keywords>
<keywords scheme="MESH" qualifier="secondary" xml:lang="en"><term>Liver Neoplasms</term>
<term>Neuroendocrine Tumors</term>
</keywords>
<keywords scheme="MESH" xml:lang="en"><term>Humans</term>
<term>Intestine, Small</term>
<term>Magnetic Resonance Imaging</term>
<term>Receptors, Somatostatin</term>
<term>Tomography, X-Ray Computed</term>
<term>Ultrasonography</term>
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<front><div type="abstract" xml:lang="en">Neuroendocrine tumours (NETs) comprise a heterogeneous group of neoplasms with very varying clinical expression. A functioning NET, for instance in the pancreas, may be very small and yet give rise to severe endocrine symptoms whereas a patient with a small bowel tumour may present with diffuse symptoms and disseminated disease with a palpable bulky liver. Imaging of NETs is therefore challenging and the imaging needs in the various patients are diverse. The basic modalities for NET imaging are computed tomography (CT) or magnetic resonance imaging (MRI) in combination with somatostatin receptor imaging (SMI) by scintigraphy with 111In-labelled octreotide (OctreoScan) or more recently by positron emission tomography (PET) with 68Ga-labelled somatostatin analogues. In this review these various morphological and functional imaging modalities and important methodological aspects are described. Imaging requirements for the various types of NETs are discussed and typical image findings are illustrated.</div>
</front>
</TEI>
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<DateCreated><Year>2013</Year>
<Month>04</Month>
<Day>15</Day>
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<DateCompleted><Year>2013</Year>
<Month>06</Month>
<Day>17</Day>
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<DateRevised><Year>2013</Year>
<Month>11</Month>
<Day>21</Day>
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<Article PubModel="Print"><Journal><ISSN IssnType="Electronic">1532-1916</ISSN>
<JournalIssue CitedMedium="Internet"><Volume>26</Volume>
<Issue>6</Issue>
<PubDate><Year>2012</Year>
<Month>Dec</Month>
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</JournalIssue>
<Title>Best practice & research. Clinical gastroenterology</Title>
<ISOAbbreviation>Best Pract Res Clin Gastroenterol</ISOAbbreviation>
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<ArticleTitle>Radiological and nuclear medicine imaging of gastroenteropancreatic neuroendocrine tumours.</ArticleTitle>
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<Abstract><AbstractText>Neuroendocrine tumours (NETs) comprise a heterogeneous group of neoplasms with very varying clinical expression. A functioning NET, for instance in the pancreas, may be very small and yet give rise to severe endocrine symptoms whereas a patient with a small bowel tumour may present with diffuse symptoms and disseminated disease with a palpable bulky liver. Imaging of NETs is therefore challenging and the imaging needs in the various patients are diverse. The basic modalities for NET imaging are computed tomography (CT) or magnetic resonance imaging (MRI) in combination with somatostatin receptor imaging (SMI) by scintigraphy with 111In-labelled octreotide (OctreoScan) or more recently by positron emission tomography (PET) with 68Ga-labelled somatostatin analogues. In this review these various morphological and functional imaging modalities and important methodological aspects are described. Imaging requirements for the various types of NETs are discussed and typical image findings are illustrated.</AbstractText>
<CopyrightInformation>Copyright © 2013 Elsevier Ltd. All rights reserved.</CopyrightInformation>
</Abstract>
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<ForeName>Anders</ForeName>
<Initials>A</Initials>
<Affiliation>Karolinska Institute and Karolinska University Hospital, SE-171 76 Stockholm, Sweden. anders.sundin@ki.se</Affiliation>
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<Language>eng</Language>
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<ChemicalList><Chemical><RegistryNumber>0</RegistryNumber>
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<MeshHeading><DescriptorName MajorTopicYN="N">Neuroendocrine Tumors</DescriptorName>
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<QualifierName MajorTopicYN="Y">diagnosis</QualifierName>
</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Positron-Emission Tomography</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N">Receptors, Somatostatin</DescriptorName>
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<MeshHeading><DescriptorName MajorTopicYN="N">Stomach Neoplasms</DescriptorName>
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</MeshHeading>
<MeshHeading><DescriptorName MajorTopicYN="N">Ultrasonography</DescriptorName>
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<Month>11</Month>
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